Table 1.
HRCT patterns and prognosis of RA-ILD.
| Authors | Year | No. of Patients | HRCT Patterns | Reference to Criteria of HRCT Classification | 5-Year Survival Rate (%) | Median Survival |
|---|---|---|---|---|---|---|
| Kim et al. [23] | 2010 | 82 | 24% (UIP) 23% (NSIP) 51% (Indeterminate) 2% (Others) |
2002 ATS/ERS classification of the IIPs | N/A | 3.2 years (UIP) 6.6 years (Non-UIP) |
| Tsuchiya et al. [42] | 2011 | 94 | 61% (UIP) 17% (NSIP) 22% (Others) |
2002 ATS/ERS classification of the IIPs | 36.6% (UIP) 93.8% (NSIP) |
3.9 years (UIP) 17 years (NSIP) |
| Kelly et al. [25] | 2014 | 230 | 65% (UIP) 24% (NSIP) 11% (Others) |
N/A | N/A | N/A |
| Solomon et al. [26] | 2016 | 137 | 79% (Definite + Possible UIP) 21% (NSIP) | 2011 IPF guideline | N/A | 10.2 years (Definite+Possible UIP) 13.6 years (NSIP) |
| Morisset et al. [43] | 2017 | 309 | 24% (Definite UIP) 16% (Possible UIP) 60% (Inconsistent with UIP) |
2011 IPF guideline | N/A | N/A |
| Zamora-Legoff et al. [20] | 2017 | 181 | 54% (UIP) 40% (NSIP) 6% (OP) |
N/A | 55.2% (UIP) 65.0% (NSIP) 47.4% (OP) |
N/A |
| Yunt et al. [44] | 2017 | 158 | 63% (Definite UIP) 15% (Possible UIP) 22% (NSIP) |
2011 IPF guideline | N/A | 8.3 years (Definite UIP) 6.1 years (Possible UIP) Incalculable (NSIP) |
| Fu et al. [45] | 2019 | 266 | 17% (Definite UIP) 20% (Possible UIP) 32% (Unclassifiable) 30% (Others) |
2011 IPF guideline | 69.7% (All) | N/A |
| Jacob et al. [46] | 2019 | 157 | 35% (Definite UIP) 36% (Probable UIP) 29% (Inconsistent with UIP) |
2018 Diagnostic criteria for IPF:
Fleischner Society |
<6-year survival rate > 45% (Definite UIP) 58% (Probable UIP) |
N/A |
| Yamakawa et al. [47] | 2019 | 112 | 21% (Definite UIP) 20% (Probable UIP) 27% (Mixed NSIP/UIP) 29% (Alternative) |
2018 IPF guideline | 70.2% (Definite UIP) 90.9% (Probable UIP) 80.0% (Mixed NSIP/UIP) 90.0% (NSIP) |
6.8 years (Definite UIP) 9.1 years (Probable UIP) 8.6 years (Mixed NSIP/UIP) 7.8 years (NSIP) |
| Kakutani et al. [5] | 2020 | 261 | 46% (Definite + Possible UIP) 54% (Non-UIP) |
2011 IPF guideline | N/A | N/A |
Abbreviations: ATS = American Thoracic Society; ERS = European Respiratory Society; HRCT = high-resolution computed tomography; IPF = idiopathic pulmonary fibrosis; NSIP = nonspecific interstitial pneumonia; OP = organizing pneumonia; RA-ILD = rheumatoid arthritis-associated interstitial lung disease; UIP = usual interstitial pneumonia.