Table 2.
Prevalence of HPV and human herpesviruses in cervicovaginal specimens of HIV-infected women.
| Virus detection | Overall (n = 236) |
hrHPV negative (n = 134) |
hrHPV positive (n = 102) |
p-valuec |
|---|---|---|---|---|
| HPV | No. (%) | No. (%) | No. (%) | |
| Any | 115 (48.7) | |||
| Low-riska | 53 (22.5) | |||
| High-riskb | 102 (43.2) | |||
| Multiple | 57 (24.2) | |||
| HPV-16 | 4 (1.7) | |||
| HHV | ||||
| Any | 47 (19.9) | 24 (17.9) | 23 (22.5) | .41 |
| HSV-1 (HHV1) | 1 (0.4) | 1 (0.7) | 0 (0) | 1.00 |
| HSV-2 (HHV2) | 15 (6.4) | 7 (5.2) | 8 (7.8) | .43 |
| EBV (HHV4) | 30 (12.7) | 16 (11.9) | 14 (13.7) | 0.70 |
| CMV (HHV5) | 0 (0) | 0 (0) | 0 (0) | N/A |
| KSHV (HHV8) | 0 (0) | 0 (0) | 0 (0) | N/A |
a
Low-risk: HPV genotypes (6, 11, 40, 42, 53, 54, 66, 84) that are rarely associated with cervical cancer.
b
High-risk: HPV genotypes (16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 55, 56, 57, 58, 59, 68, 73, 82, 83) that have been associated with cervical cancer.
c
Fisher’s Exact Test p-value is presented.
Abbreviations: hrHPV, high-risk HPV. HPV, human papillomavirus. HHV, human herpesvirus. HSV-1, herpes simplex virus-1. HSV-2, herpes simplex virus-2. EBV, Epstein-Barr virus. CMV, cytomegalovirus. KSHV, Kaposi’s sarcoma herpesvirus.