Table 4.
Risk factorsa for EBV detection in cervicovaginal lavage of HIV-positive women who are also hrHPV-positive (n=102).
| EBV Negative (n = 88) |
EBV Positive (n = 14) |
p-valueb | |
|---|---|---|---|
| Race/Ethnicity | .693 | ||
| Caucasian | 10 (11.4) | 1 (7.7) | |
| African-American | 78 (88.6) | 12 (92.3) | |
| Hispanic | (N/A) | (N/A) | |
| Age | .298 | ||
| 20-30 | 31 (35.2) | 2 (14.3) | |
| 31-40 | 33 (37.5) | 7 (50.0) | |
| >40 | 23 (26.1) | 5 (35.7) | |
| Mean | 34.8 | 37.8 | .195 |
| Marital status | .917 | ||
| Married/co-habitant partner | 7 (8.0) | 1 (7.1) | |
| Single/divorced/widowed | 81 (92.0) | 13 (92.9) | |
| Education level | .254 | ||
| 6-11 years | 8 (9.5) | 3 (21.4) | |
| High School graduate | 68 (80.9) | 8 (57.1) | |
| College graduate or above | 8 (9.5) | 3 (21.4) | |
| Smoking history | .939 | ||
| Never | 45 (51.1) | 7 (50.0) | |
| Ever | 43 (48.9) | 7 (50.0) | |
| Parity | .298 | ||
| Nulliparous | 6 (7.3) | 0 (0) | |
| ≥ 1 | 76 (92.7) | 14 (100) | |
| History of abnormal Pap smear | .012 | ||
| Yes | 49 (65.3) | 11 (78.6) | |
| No | 26 (34.7) | 3 (21.4) | |
| Male sex partners in past year | .644 | ||
| None | 9 (13.0) | 2 (22.2) | |
| 1 | 41 (59.4) | 4 (44.4) | |
| 2 or more | 19 (27.5) | 3 (33.4) | |
| Male sex partners in past month | .712 | ||
| None | 16 (27.6) | 3 (37.5) | |
| 1 | 39 (67.2) | 5 (62.5) | |
| 2 or more | 3 (5.2) | 0 (0) | |
| CD4+ T cell count | .980 | ||
| <200 | 24 (27.9) | 4 (28.6) | |
| 200-500 | 33 (38.3) | 5 (35.7) | |
| >500 | 29 (33.7) | 5 (35.7) | |
| Mean | 398 | 401 | .673 |
| Peripheral HIV viral load | .895 | ||
| <400 | 24 (27.9) | 2 (14.3) | |
| 400-10,000 | 25 (29.0) | 5 (35.7) | |
| >10,000 | 37 (43.0) | 7 (50.0) | |
| Mean | 95,408 | 53,384 | .450 |
a
All data is self-reported on demographic survey, except CD4+ T cell counts and peripheral HIV viral load which were extracted from the clinical chart.
b
Probability (p) was derived from Chi square analysis, or Fisher Exact test as appropriate.
Abbreviations: HIV, human immunodeficiency virus. EBV, Epstein-Barr virus. hrHPV, high-risk HPV.