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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Leuk Lymphoma. 2021 Apr 11;62(5):1167–1177. doi: 10.1080/10428194.2021.1910684

Figure 1. JAK/STAT and BCL2 pathways are dysregulated in T-ALL.

Figure 1.

(A-C) Histograms of T-ALL lines Jurkat and Loucy stained for pSTAT1 (A), pSTAT3 (B) or BCL2 (C) and compared to healthy controls and an isotype control antibody. Bar graphs represent the fold MFI (target MFI / isotype MFI) of two independent experiments (for cancer lines) and two healthy donors. (D-F) Normalized FPKM values of STAT1 (D), STAT3 (E) and BCL2 (F) at diagnosis and relapse from a Children’s Oncology Group T-ALL RNA-seq dataset(26).