Table 3. Bivariate and multivariate analyses considering men who have sex with men (n: 1,301) reporting chemsex during the COVID-19 pandemic. Portugal, 2020.

Variables	OR*	p-value†	95%CI‡	aOR§	p-value†	95%CI‡
Sociodemographic characteristics
Current relationship
Stable	1
Polyamory/open	0,52	0,145	0,22 – 1,25
Single	1,79	0,007	1,17 – 2,75
Live with sexual partner
Yes	1
No	2,42	0,001	1,44 – 4,07
Live in the metropolitan area
No	1
Yes	1,99	0,030	1,04 – 3,79
Use dating apps to seek partners
No	1
Yes	1,49	0,022	1,06 – 2,09
Sexual health
HIV‖ Status
Unknown	1
HIV‖ -	2,92	0,001	1,58 – 5,39
HIV‖ +	2,50	0,005	1,27 – 4,91
During the social distancing period Group sex (with 2 or more people simultaneously)
Sexo en grupo (simultáneo con 2 o más personas)
No
Yes	41,78	0,001	27,52 – 63,41	28,4	0,001	16,93 – 47,49
Sex with penetration without condoms
No
Yes	9,31	0,001	6,84 – 12,67	7,1	0,001	4,57 – 10,99
Paid for sexual intercourse
No	1
Yes	1,85	0,040	1,01 – 3,40
Protective measures against the COVID-19 adopted during casual sex
Disinfected the place where you had sex
No	1
Yes	1,45	0,018	1,06 – 1,97
Avoided kissing during sexual intercourse?
No	1
Yes	1,58	0,003	1,16 – 2,15
Verified whether the sexual partner had signs and symptoms of COVID-19
No	1
Yes	1,41	0,031	1,03 – 1,95
Used PrEP ¶ / Truvada
No	1
Yes	4,34	0,001	3,03 – 6,23	4,2	0,001	2,71 – 6,39
COVID-19 Investigation
COVID-19 testing
No	1
Yes	2,40	0,001	1,76 – 3,27	1,9	0,012	1,15 – 3,10

^**OR = Odds Ratio; ^†p = Statistical significance; ^‡95%CI = 95% Confidence Interval; ^§aOR = adjusted Odds Ratio; ^||HIV = Human Immunodeficiency Virus; ^¶PrEP = Pre-exposure prophylaxis. Hosmer and Lemeshow test (p=0.61)