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. Author manuscript; available in PMC: 2022 Mar 2.
Published in final edited form as: Nat Genet. 2021 Sep 2;53(9):1300–1310. doi: 10.1038/s41588-021-00913-z

Figure 5. SNPs associated with systemic lupus erythematosus (SLE) converge on a shared cluster of interferon-response genes.

Figure 5.

The genes shown are those affected by at least three independent GWAS SNPs. SNPs in the HLA region are not visualized and SNPs in partial linkage disequilibrium are grouped together. The heatmap indicates the direction and strength of individual trans-eQTL effects (Z-scores), relative to the SLE risk allele.