Table 1. Comparison of different background correction methods on correlation between y-axis location and probe intensity.
Array | Raw | Subtracted | Scaled | Scaling > Subtraction | |||
---|---|---|---|---|---|---|---|
Pearson r | p-value | Pearson r | p-value | Pearson r | p-value | ||
S1 Day 1 | 0.310 | 5.10E-69 | 0.065 | 4.30E-04 | 0.0002 | 0.990 | TRUE |
S1 Day 2 | 0.110 | 1.10E-09 | 0.025 | 0.170 | -0.0013 | 0.940 | TRUE |
S1 Day 3 | 0.170 | 5.40E-22 | 0.034 | 0.061 | 0.0130 | 0.480 | TRUE |
S2 Day 1 | 0.230 | 8.60E-39 | 0.023 | 0.200 | -0.0320 | 0.079 | FALSE |
S2 Day 2 | 0.110 | 4.80E-09 | 0.047 | 0.010 | 0.0590 | 0.001 | FALSE |
S2 Day 3 | 0.043 | 1.80E-02 | 0.056 | 0.002 | 0.0610 | 0.001 | FALSE |
S3 Day 1 | -0.110 | 2.60E-09 | -0.026 | 0.150 | -0.0027 | 0.880 | TRUE |
S3 Day 2 | 0.330 | 4.80E-80 | 0.110 | 9.20E-10 | -0.0013 | 0.940 | TRUE |
S3 Day 3 | -0.071 | 9.90E-05 | 0.039 | 0.033 | 0.0710 | 8.80E-05 | FALSE |
S4 Day 1 | 0.240 | 1.70E-41 | 0.028 | 0.13 | -0.0350 | 0.058 | FALSE |
S4 Day 2 | 0.190 | 3.40E-27 | 0.100 | 7.40E-09 | 0.0730 | 5.70E-05 | TRUE |
S4 Day 3 | 0.210 | 2.80E-31 | 0.086 | 2.30E-06 | 0.0420 | 0.022 | TRUE |
S5 Day 1 | 0.160 | 3.80E-18 | 0.024 | 1.80E-01 | -0.0072 | 6.90E-01 | TRUE |
S5 Day 2 | 0.280 | 1.20E-54 | 0.130 | 2.80E-12 | 0.0650 | 0.000 | TRUE |
S5 Day 3 | 0.170 | 3.00E-21 | 0.030 | 9.50E-02 | -0.0110 | 0.560 | TRUE |
S6 Day 1 | 0.370 | 6.50E-99 | 0.033 | 6.90E-02 | -0.0320 | 0.078 | TRUE |
S6 Day 2 | 0.330 | 5.30E-78 | 0.051 | 0.0052 | -0.0080 | 0.660 | TRUE |
S6 Day 3 | -0.021 | 2.40E-01 | -0.082 | 6.60E-06 | -0.1000 | 8.60E-09 | FALSE |
S7 Day 1 | 0.330 | 1.30E-75 | 0.075 | 3.70E-05 | -0.0090 | 0.620 | TRUE |
S7 Day 2 | -0.180 | 1.50E-23 | 0.060 | 9.40E-04 | 0.0370 | 0.042 | TRUE |
S7 Day 3 | 0.090 | 6.40E-07 | 0.005 | 0.790 | -0.0280 | 0.120 | FALSE |
S8 Day 1 | 0.260 | 1.60E-47 | 0.028 | 1.20E-01 | -0.0210 | 0.250 | TRUE |
S8 Day 2 | 0.240 | 1.30E-40 | 0.072 | 7.50E-05 | 0.0240 | 0.180 | TRUE |
S8 Day 3 | 0.220 | 1.30E-34 | 0.055 | 2.50E-03 | -0.0150 | 0.400 | TRUE |
S9 Day 1 | 0.360 | 3.70E-94 | 0.062 | 6.60E-04 | 0.0240 | 0.180 | TRUE |
S9 Day 2 | 0.330 | 1.10E-76 | 0.059 | 1.20E-03 | 0.0150 | 0.440 | TRUE |
S9 Day 3 | 0.270 | 9.20E-52 | 0.095 | 1.90E-07 | 0.0250 | 0.170 | TRUE |
Average | 0.212 | 1.38E-39 | 0.056 | 0.001 | 0.030 | 0.039 | 0.741 |