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. 2021 Sep 10;16(9):e0257232. doi: 10.1371/journal.pone.0257232

Table 1. Comparison of different background correction methods on correlation between y-axis location and probe intensity.

Array Raw Subtracted Scaled Scaling > Subtraction
Pearson r p-value Pearson r p-value Pearson r p-value
S1 Day 1 0.310 5.10E-69 0.065 4.30E-04 0.0002 0.990 TRUE
S1 Day 2 0.110 1.10E-09 0.025 0.170 -0.0013 0.940 TRUE
S1 Day 3 0.170 5.40E-22 0.034 0.061 0.0130 0.480 TRUE
S2 Day 1 0.230 8.60E-39 0.023 0.200 -0.0320 0.079 FALSE
S2 Day 2 0.110 4.80E-09 0.047 0.010 0.0590 0.001 FALSE
S2 Day 3 0.043 1.80E-02 0.056 0.002 0.0610 0.001 FALSE
S3 Day 1 -0.110 2.60E-09 -0.026 0.150 -0.0027 0.880 TRUE
S3 Day 2 0.330 4.80E-80 0.110 9.20E-10 -0.0013 0.940 TRUE
S3 Day 3 -0.071 9.90E-05 0.039 0.033 0.0710 8.80E-05 FALSE
S4 Day 1 0.240 1.70E-41 0.028 0.13 -0.0350 0.058 FALSE
S4 Day 2 0.190 3.40E-27 0.100 7.40E-09 0.0730 5.70E-05 TRUE
S4 Day 3 0.210 2.80E-31 0.086 2.30E-06 0.0420 0.022 TRUE
S5 Day 1 0.160 3.80E-18 0.024 1.80E-01 -0.0072 6.90E-01 TRUE
S5 Day 2 0.280 1.20E-54 0.130 2.80E-12 0.0650 0.000 TRUE
S5 Day 3 0.170 3.00E-21 0.030 9.50E-02 -0.0110 0.560 TRUE
S6 Day 1 0.370 6.50E-99 0.033 6.90E-02 -0.0320 0.078 TRUE
S6 Day 2 0.330 5.30E-78 0.051 0.0052 -0.0080 0.660 TRUE
S6 Day 3 -0.021 2.40E-01 -0.082 6.60E-06 -0.1000 8.60E-09 FALSE
S7 Day 1 0.330 1.30E-75 0.075 3.70E-05 -0.0090 0.620 TRUE
S7 Day 2 -0.180 1.50E-23 0.060 9.40E-04 0.0370 0.042 TRUE
S7 Day 3 0.090 6.40E-07 0.005 0.790 -0.0280 0.120 FALSE
S8 Day 1 0.260 1.60E-47 0.028 1.20E-01 -0.0210 0.250 TRUE
S8 Day 2 0.240 1.30E-40 0.072 7.50E-05 0.0240 0.180 TRUE
S8 Day 3 0.220 1.30E-34 0.055 2.50E-03 -0.0150 0.400 TRUE
S9 Day 1 0.360 3.70E-94 0.062 6.60E-04 0.0240 0.180 TRUE
S9 Day 2 0.330 1.10E-76 0.059 1.20E-03 0.0150 0.440 TRUE
S9 Day 3 0.270 9.20E-52 0.095 1.90E-07 0.0250 0.170 TRUE
Average 0.212 1.38E-39 0.056 0.001 0.030 0.039 0.741