Table 3.
BP control by region in ENCHANTED.
| Western countries | China | Other asian | South America | P -value | ||
|---|---|---|---|---|---|---|
| Achieved mean SBP | ||||||
| Within 1 h | 158 (157–160) | 152 (150–153) | 153 (151–155) | 154 (152–156) | <0.0001 | |
| Within 6 h | 155 (154–157) | 150 (149–151) | 150 (148–152) | 152 (151–154) | <0.0001 | |
| Within 12 h | 152 (151–153) | 149 (147–150) | 148 (146–150) | 151 (149–152) | <0.0001 | |
| Within 24 h | 149 (147–150) | 147 (146–148) | 146 (144–147) | 149 (148–151) | 0.0005 | |
| 1–24 h | 139 (138–141) | 142 (141–144) | 138 (136–140) | 145 (143–146) | <0.0001 | |
| 2–7 days | 138 (137–140) | 141 (139–142) | 136 (134–138) | 140 (139–142) | <0.0001 | |
| Magnitude of SBP reduction | ||||||
| Within 1 h | 23 (21–25) | 22 (20–25) | 24 (22–26) | 18 (16–20) | <0.0001 | |
| Within 6 h | 29 (28–31) | 29 (28–31) | 31 (29–33) | 31 (29–33) | 0.082 | |
| Within 12 h | 36 (34–37) | 33 (31–34) | 35 (33–37) | 35 (33–37) | 0.0007 | |
| Within 24 h | 40 (39–42) | 36 (34–37) | 38 (36–40) | 38 (37–40) | <0.0001 | |
| 1–24 h | 39 (37–41) | 34 (33–36) | 37 (35–39) | 36 (34–38) | <0.0001 | |
| 2–7days | 37 (35–39) | 37 (35–38) | 42 (40–44) | 40 (38–42) | <0.0001 | |
| Maximum SBP | ||||||
| Within 1 h | 170 (168–172) | 161 (160–163) | 164 (161–166) | 166 (164–168) | <0.0001 | |
| Within 6 h | 171 (169–173) | 163 (161–164) | 164 (162–167) | 168 (166–170) | <0.0001 | |
| Within 12 h | 171 (170–173) | 163 (162–165) | 165 (163–167) | 169 (167–171) | <0.0001 | |
| Within 24 h | 172 (171–174) | 165 (163–166) | 166 (163–168) | 171 (169–173) | <0.0001 | |
| 1–24 h | 163 (161–165) | 157 (156–159) | 155 (153–158) | 164 (162–166) | <0.0001 | |
| 2–7 days | 148 (147–150) | 153 (151–154) | 148 (146–150) | 156 (154–157) | <0.0001 | |
| Minimum SBP | ||||||
| Within 1 h | 147 (145–149) | 142 (141–144) | 143 (141–145) | 141 (139–143) | <0.0001 | |
| Within 6 h | 136 (134–138) | 136 (135–138) | 134 (132–136) | 134 (132–136) | 0.082 | |
| Within 12 h | 130 (128–131) | 133 (131–134) | 130 (128–132) | 130 (128–132) | 0.0007 | |
| Within 24 h | 125 (123–127) | 129 (128–131) | 127 (125–129) | 127 (125–129) | <0.0001 | |
| 1–24 h | 126 (124–128) | 131 (129–132) | 128 (126–130) | 129 (127–131) | <0.0001 | |
| 2–7 days | 128 (126–130) | 129 (127–130) | 123 (121–126) | 125 (124–127) | <0.0001 | |
| SBP variability (standard deviation) | ||||||
| Within 1 h | 9 (8–9) | 10 (9–11) | 11 (11–12) | 11 (11–12) | <0.0001 | |
| Within 6 h | 15 (14–16) | 11 (10–11) | 13 (12–14) | 14 (13–15) | <0.0001 | |
| Within 12 h | 17 (16–17) | 12 (11–12) | 14 (13–15) | 15 (14–16) | <0.0001 | |
| Within 24 h | 17 (17–18) | 12 (12–13) | 14 (13–15) | 15 (15–16) | <0.0001 | |
| 1–24 h | 15 (14–16) | 11 (10–11) | 11 (10–12) | 14 (13–15) | <0.0001 | |
| 2–7 days | 10 (9–11) | 9 (9–10) | 11 (10–12) | 12 (12–13) | <0.0001 |
Data are mean (SD), or median (IQR). P-values are based on T-test, or Wilcoxon signed-rank test.
BP, blood pressure, SBP, systolic blood pressure.