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. 2021 Sep 10;35(3):171–180. doi: 10.1055/s-0041-1731463

Table 2. Cellular skin substitutes.

Product Manufacturer Replaced region
Human-derived grafts
 SkinTE PolarityTE, Salt Lake City, UT Epidermal/dermal
 TheraSkin LifeNet Health, Virginia Beach, VA (procurement and processing) Solsys Medical, Newport News, VA (distribution) Epidermal/dermal
Human amnion chorion membrane grafts
 Affinity Human Amniotic Allograft Organogenesis, Inc., Canton, MA Dermal
 FlōGraft Amniotic Fluid-Derived Allograft Applied Biologics, Scottsdale, AZ Dermal
 Grafix Osiris Therapeutics, Inc., Columbia, MD Dermal
 GrafixPL Prime Osiris Therapeutics, Inc., Columbia, MD Dermal
Combined human and animal grafts
 Apligraf Organogenesis, Inc., Canton, MA Epidermal/dermal
Synthetic grafts
 Hyalomatrix tissue reconstruction matrix Anika Therapeutics, Bedford, MA Dermal
 Restrata Acera Surgical, Inc., St. Louis, MO Dermal
Combined natural and synthetic grafts
 Dermagraft Organogenesis, Inc., Canton, MA Dermal