Table 2.
Univariate logistic regression analysis of risk factors for critical COVID-19.
| Variables | OR (95% CI) | p-valuea |
|---|---|---|
| Age ≥65 y | 3.68 (2.18–6.21) | <0.001 |
| Male sex | 1.99 (1.15–3.44) | 0.014 |
| Body mass index of ≥25 kg/m2 | 1.38 (0.83–2.32) | 0.22 |
| Current smoker | 0.74 (0.30–1.78) | 0.50 |
| Brinkman index of ≥600 | 1.91 (1.02–3.55) | 0.042 |
| Hypertension | 2.70 (1.60–4.56) | <0.001 |
| Diabetes | 3.39 (1.95–5.87) | <0.001 |
| Cancerb | 0.94 (0.40–2.22) | 0.89 |
| Chronic heart diseases | 1.94 (0.95–3.97) | 0.069 |
| Hemodialysis | 5.75 (2.23–14.8) | <0.001 |
| COPD | 1.90 (0.42–8.66) | 0.41 |
| ILD | 1.67 (0.28–10.2) | 0.58 |
| Need for O2 supplementation upon diagnosis | 12.1 (5.88–25.0) | <0.001 |
| CRP level of ≥6.5 mg/dL | 5.55 (3.24–9.54) | <0.001 |
COVID-19: coronavirus disease 2019, OR: odds ratio, CI: confidence interval, COPD: chronic obstructive pulmonary disease, ILD: interstitial lung disease, CRP: C-reactive protein.
a
Univariate logistic regression analysis was used to compare the variables between the critical and non-critical groups.
b
Cancer types included genitourinary (11 cases), gastrointestinal (7 cases), breast (7 cases), lung (4 cases), gynecologic (2 cases), and head and neck (2 cases) cancers. Four patients had histories of two cancers.