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. 2021 Sep 11;24(10):103120. doi: 10.1016/j.isci.2021.103120

Table 2.

EC50 Values of HUP1108 (HMTU) against flaviviruses

Virus Cell line Time Assay HUP1108 EC50 (μM) Ribavirin EC50 (μM) Favipiravir EC50 (μM)
DENV1 BHK-21 5 days Resazurin 0.35 62 17
DENV2 BHK-21 4 days Resazurin 0.24 19 4.4
DENV3 BHK-21 5 days Resazurin 0.42 54 13
DENV4 BHK-21 5 days Resazurin 0.52 86 5.2
ZIKV BHK-21 3 days MTT 1.3 31 40
YFV BHK-21 3 days MTT 0.27 34 57
JEV BHK-21 3 days MTT 0.50 33 80
WNV BHK-21 3 days MTT 0.95 52 >100