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. 2021 Jan 27;258(5):935–948. doi: 10.1007/s00709-021-01613-5

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© The Author(s) 2021

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Fig. 5 — Content of cells with reactive oxygen species (ROS) in Ab and B16F10 melanoma cultured in RPMI or DMEM. Cells treated with H₂O₂ to a final concentration of 50 μM serve as a positive control (PC) of ROS presence. Asterisk indicates a statistically significant change compared with time 0; p≤0.05, nonparametric Jonckheere trend test; means data ± SD of 4 independent experiments for each cell line