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. Author manuscript; available in PMC: 2023 Oct 1.
Published in final edited form as: Exp Clin Psychopharmacol. 2021 Mar 11;30(5):593–608. doi: 10.1037/pha0000454

Table 2.

Indirect effects of co-use motives on co-use consequences via multiple alcohol and cannabis product usage

Effect Enhancement Motives Social Motives Offered Motives Coping Motives

Outcome/Mediator IE 95% CI IE 95% CI IE 95% CI IE 95% CI

Level-1 Effects

Number of consequences
 # of Alcohol products 0.02* [0.007, 0.041] 0.03* [0.014, 0.039] 0.02* [0.008, 0.029] 0.01 [−0.003, 0.023]
 # of Cannabis products 0.01 [−0.001, 0.022] 0.00 [0.000, 0.009] 0.00 [0.000, 0.010] 0.01 [0.000, 0.015]
Nausea
 # of Alcohol products 0.07* [0.022, 0.148] 0.09* [0.047, 0.144] 0.06* [0.027, 0.102] 0.03 [−0.009, 0.082]
 # of Cannabis products 0.02 [−0.023, 0.063] 0.01 [−0.007, 0.025] 0.01 [−0.008, 0.029] 0.01 [−0.011, 0.044]
Hangover
 # of Alcohol products 0.03* [0.002, 0.074] 0.03 [−0.001, 0.072] 0.02* [0.003, 0.054] 0.01 [−0.004, 0.040]
 # of Cannabis products 0.02 [−0.011, 0.061] 0.01 [−0.004, 0.023] 0.03 [−0.010, 0.107] 0.01 [−0.006, 0.040]
Blackout
 # of Alcohol products 0.07* [0.017, 0.159] 0.09* [0.035, 0.160] 0.06* [0.020, 0.113] 0.03 [−0.008, 0.082]
 # of Cannabis products 0.03 [−0.022, 0.095] 0.01 [−0.009, 0.036] 0.01 [−0.009, 0.041] 0.01 [−0.016, 0.059]

Level-2 Effects

Number of consequences
 # of Alcohol products 0.01 [−0.020, 0.044] 0.01 [−0.015, 0.037] 0.00 [−0.010, 0.024] 0.00 [−0.011, 0.024]
 # of Cannabis products 0.01 [−0.019, 0.048] 0.00 [−0.006, 0.014] 0.00 [−0.008, 0.010] 0.00 [−0.010, 0.027]
Nausea
 # of Alcohol products 0.01 [−0.079, 0.112] 0.01 [−0.065, 0.091] 0.01 [−0.040, 0.060] 0.00 [−0.036, 0.062]
 # of Cannabis products 0.00 [−0.089, 0.095] 0.00 [−0.022, 0.025] 0.00 [−0.020, 0.020] 0.00 [−0.043, 0.049]
Hangover
 # of Alcohol products 0.05 [−0.023, 0.189] 0.07 [−0.004, 0.168] 0.01 [−0.004, 0.026] 0.01 [−0.036, 0.106]
 # of Cannabis products −0.02 [−0.132, 0.073] −0.00 [−0.032, 0.022] 0.00 [−0.025, 0.021] −0.00 [−0.065, 0.039]
Blackout
 # of Alcohol products 0.01 [−0.138, 0.177] 0.02 [−0.110, 0.153] 0.01 [−0.061, 0.107] 0.00 [−0.064, 0.101]
 # of Cannabis products 0.04 [−0.083, 0.214] 0.00 [−0.025, 0.061] 0.00 [−0.034, 0.043] 0.01 [−0.046, 0.118]

Note. IE = indirect effect; 95% CI = 95% Bayesian credibility interval. Level-1 = within-person; Level-2 = between-person. Nausea, hangover, and blackout modeled as binary (yes/no). All models include the following covariates: age, sex, school (recruitment site), day of the week, other drug use, number of drinks, and number of cannabis uses. IEs are unstandardized.

*

indicate significant effects, such that credibility intervals do not overlap zero.