TABLE 2.
Association of clinicopathologic factors with retroperitoneal and/or pelvic LN radiographic persistence
| Univariate regression | ||
|---|---|---|
| OR (95% CI) | p value | |
| Age at diagnosis (median, IQR) | 0.98 (0.85–1.02) | .40 |
| Sex | ||
| Male | Reference | |
| Female | 1.23 (0.50–3.07) | .64 |
| Race | ||
| White | Reference | |
| Black | 0.31 (0.08–1.13) | .08 |
| Other | 0.52 (0.04–10.30) | .74 |
| Functional status | ||
| Independent | Reference | |
| Partially dependent | - | |
| Pretreatment stage (AJCC 8th ed) | ||
| I | Reference | |
| II | - | |
| III | - | |
| Pretreatment tumor location | ||
| Lower rectum | Reference | |
| Middle rectum | 0.69 (0.26–1.83) | .46 |
| Upper rectum | 0.55 (0.07–4.38) | .57 |
| Neoadjuvant chemotherapy | ||
| No | Reference | |
| Yes | - | |
| Neoadjuvant chemoradiation | ||
| No | Reference | |
| Yes | - | |
| Total neoadjuvant therapy | ||
| No | Reference | |
| Yes | 0.21 (0.08–0.55) | <.01 |
Abbreviations: AJCC, American Joint Committee on Cancer; LAR, low anterior resection; CI, confidence interval; IQR, interquartile range; LN, lymph node; OR, odds ratio.