TABLE 1.
Cell cycle analysis of thymocytes from 4-week-old micea
| Genotype | Total thymocytes
|
CD4+ thymocytes
|
CD4− thymocytes
|
|||
|---|---|---|---|---|---|---|
| G0/G1 | S+G2 | G0/G1 | S+G2 | G0/G1 | S+G2 | |
| −/− | 94.1 ± 1.1 | 5.9 ± 1.1 | 94.4 ± 0.4 | 5.6 ± 0.4 | 94.0 ± 2.4 | 6.0 ± 2.4 |
| LMO1/− | 94.6 ± 1.7 | 5.4 ± 1.7 | 94.6 ± 2.0 | 5.4 ± 2.0 | 93.4 ± 1.2 | 6.6 ± 1.2 |
| SCL/− | 94.6 ± 1.1 | 5.5 ± 1.1 | 94.4 ± 1.2 | 5.6 ± 1.2 | 94.7 ± 2.8 | 5.3 ± 2.8 |
| LMO1/SCL | 87.5 ± 2.8* | 12.5 ± 2.8* | 91.7 ± 5.0 | 8.3 ± 5.0 | 85.9 ± 0.8* | 14.1 ± 0.8* |
a
Asterisks indicate a P value of <0.005 compared to −/− control thymocytes. CD4+ and CD4− refer to thymocytes that are positive or negative for CD4 expression. Values shown are the mean percentages ± the standard deviation for at least four mice.