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Experimental design and variant calling results summary. (A) Timeline of heart tissue collected for subsequent sequencing and variant calling. (B) SNP counts per each of the considered aging mouse models (n = 4 for each model). NA12W, natural aging 12-wk old; NA52W, natural aging 52-wk old; and NA104W, natural aging 104-wk old. Data are represented as mean ± SEM * indicates P < 0.0001 versus NA12W.
