Table 4.
Subgroup analyses of the models in the whole cohort
|
|
The clinical model
|
The combined model
|
P
value
|
||||
|
Subgroups
|
AUC
|
SEN (%)
|
SPE (%)
|
AUC
|
SEN (%)
|
SPE (%)
|
|
| nCRT | |||||||
| With (n = 62) | 0.710 (0.581-0.818) | 68.00 | 75.68 | 0.853 (0.740-0.930) | 68.00 | 89.19 | 0.011 |
| Without (n = 241) | 0.712 (0.650-0.768) | 48.74 | 83.61 | 0.814 (0.759-0.861) | 65.55 | 87.70 | < 0.001 |
| Stage | |||||||
| II (n = 62) | 0.553 (0.422-0.680) | 21.05 | 93.02 | 0.670 (0.538-0.784) | 36.84 | 100.00 | 0.098 |
| III (n = 193) | 0.630 (0.558-0.698) | 56.52 | 69.23 | 0.796 (0.732-0.851) | 73.04 | 79.49 | < 0.001 |
P value: Comparisons between the clinical model and combined model. AUC: Area under the receiver operating characteristic curve; SEN: Sensitivity; SPE: Specificity; nCRT: Neoadjuvant chemoradiotherapy.