Table 2.
Summary of the different receptor-based web tools further discussed in the review (access date: 1 June 2021).
| Web Tool | Description | URL |
|---|---|---|
| INVDOCK | Reverse docking approach using an in-house database | http://bidd.group/group/softwares/invdock.htm |
| idTarget | Reverse docking approach based on Divide-and-conquer method and using all protein structures in the PDB | http://idtarget.rcas.sinica.edu.tw |
| TarFisDock | Reverse docking using the Potential Drug Target Database (PDTD) | http://www.dddc.ac.cn/tarfisdock |
| DPDR-CPI | Reverse docking using proteins from PDB and PDBBind, combined with ML models for target predictions | http://cpi.bio-x.cn/dpdr |
| ACID | Reverse docking with an automated consensus inverse docking protocol | http://chemyang.ccnu.edu.cn/ccb/server/ACID |
| DIA-DB | Identification of potential antidiabetic drugs based on similarity search and reverse docking | http://bio-hpc.eu/software/dia-db |
| GUT-DOCK | Identification of small-molecule interactions with gut hormone GPCRs based on reverse docking | https://gut-dock.miningmembrane.com |
| Drug ReposER | Pharmacophore approach based on sub-structural similarity to the binding interfaces of known drug binding sites. | http://mfrlab.org/drugreposer/ |
| LigAdvisor | 2D ligand-receptor interactions based on similarity estimations | https://ligadvisor.unimore.it |
| PLIP | Binding site alignment or similarity among molecular structures and residue sequences | https://projects.biotec.tu-dresden.de/plip-web |
| PharmMapper | Target identification based on pharmacophore mapping procedure | http://59.78.96.61/pharmmapper |