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(A) Schematic potency trends are given on the basis of studies by McClure et al. [114] (green), Wang et al. [109] (black), and Li et al. [110,111] (blue). (B) Li et al. [111] through docking suggested the binding mode of hydrazides with the zinc ion as a gray sphere and metal bonds indicated as dotted orange lines. Substitutions are indicated by spheres.
