Figure 2.

Human coagulation factor IXa and factor Xa sequence comparison were performed to identify the conserved residues within these two sets of proteins. There are 12 rows in this alignment representing 12 proteins. The first 6 are FIXa and next 6 are FXa. The dots represent the identical residues. The residues marked green indicates that they are within the distance of 3 Å from their corresponding ligands. Similarly, cyan represents residues within 4 Å and orange within 5 Å distance.