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Preparation of GOX-MPO-DS and proposed bacteria-mediated switch-on mechanism: (A) Encapsulation of GOX and MPO within a vesicle composed of AJDs to produce the antibacterial nanoreactor GOX-MPO-DS, which produces −OCl to kill Gram-positive S. aureus and Gram-negative P. aeruginosa upon addition of glucose and (B) Introduction of a bacterial switch-on mechanism enabled by the toxin-induced release of glucose from giant unilamellar vesicles [105] (Reprinted with permission from [105]).
