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(a) Schematic illustration of the production of HIONPs using a one-pot method and the GSH-responsive transformation; (b) schematic illustration of GSH-responsive magnetic HIONPs for exceedingly sensitive diagnosis of liver metastases; and (c) GSH-mediated conversion of HIONPs in metastasis tumor (non-aggregation state) and liver (aggregation state). Figure adapted with permission from [64], Copyright 2021 American Chemical Society.
