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. 2021 Sep 3;13(17):2989. doi: 10.3390/polym13172989

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(1) Illustration of PET/MRI probe based on iron oxide nanoparticle. (2) Decay-corrected whole-body coronal PET images of nude mouse bearing human U87MG tumor at 1, 4, and 21 h after injection of different PET/MRI probes based on iron oxide nanoparticles. (3) T2-weighted MR images of nude mice bearing U87MG tumor before injection of iron oxide nanoparticles (A,E) and at 4 h after tail-vein injection of DOTA-IO (B,F), DOTA-IO-RGD (C,G), and DOTA-IO-RGD with blocking dose of c(RGDyK) (D,H). Figure adapted from [103], Copyright 2008 Society of Nuclear Medicine, Inc.