Table 2.
Univariable and multivariable regression using the modified PRISMA-NMA
| Covariates | Interpretation of the coefficient | Coefficient (95% CI) | Sample size |
|---|---|---|---|
| Univariable analyses and subgroups | |||
| Published after 2015 vs until 2015 | Average increase in the score after 2015 | 1.25 (0.59, 1.91) |
Before 2015: 389 After 2015: 755 |
| Year of publication, subgroup: only NMAs published before 2015 | Average increase in the score per year | 0.96 (0.32, 1.59) | |
| Year of publication, subgroup: only NMAs published after 2015 | Average increase in the score per year | 0.53 (0.02, 1.04) | |
| Multivariable analyses with year as a continuous variable | |||
| Year of publication | Average increase in the score per year | 0.34 (0.16, 0.52) |
Year 2013: 91 (reference group) Year 2014: 104 Year 2015: 194 Year 2016: 198 Year 2017: 316 Year 2018: 241 |
| Treatment type | Average increase in the score if network includes pharmacological treatments | − 0.66 (− 1.34, 0.02) |
Pharmacological treatments: 907 Non-pharmacological treatments (reference group): 237 |
| Funding type | Average increase in the score if non-sponsored/publicly sponsored | 1.34 (0.56, 2.11) |
Non-sponsored/publicly sponsored/not reported: 974 Industry/mixed sponsored (reference group): 170 |
| Review type | Average increase in the score if protocol is not available/reported | − 5.12 (− 5.74, − 4.49) |
With protocol (reference group): 313 Without protocol: 831 |
| Impact factor | Average increase in the score per impact factor increase (1 unit) | 0.10 (0.07, 0.13) | |
| Multivariable analyses with year as a dichotomous variable | |||
| Year of publication | Average increase in the score per year | 0.81 (0.23, 1.39) |
Before 2015 (reference group):389 After 2015:755 |
| Treatment type | Average increase in the score if network includes pharmacological treatments | − 0.72 (− 1.40, − 0.04) |
Pharmacological treatments: 907 Non-pharmacological treatments (reference group): 237 |
| Funding type | Average increase in the score if non-sponsored/publicly sponsored | 1.36 (0.58, 2.14) |
Non-sponsored/publicly sponsored/Not reported: 974 Industry/mixed sponsored (reference group): 170 |
| Review type | Average increase in the score if protocol is not available/reported | − 5.18 (− 5.8, − 4.55) |
With protocol (reference group): 313 Without protocol: 831 |
| Impact factor | Average increase in the score per impact factor increase (1 unit) | 0.10 (0.06, 0.13) | |
CI confidence interval