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. 2021 Sep 10;62(12):8. doi: 10.1167/iovs.62.12.8

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Figure 4. — Rescue of retinal function in rd1 mice after AAV8-hOXR1 injection at P10. Eyes of rd1 mice were injected with AAV8-hOXR1 vector and BSS at P10 via subretinal route. Scotopic and photopic ERGs were recorded at 4, 6, 8, and 10 weeks post-injection (A) Scotopic a-wave and b-wave ERG responses are presented in box-whisker plots (n = 8–15 eyes BSS injection and n = 8–11 eyes AAV8-hOXR1 injection). (B) Photopic b-wave amplitudes are shown in box-whisker plots (n = 8–11 eyes for BSS injection and n = 8–14 eyes for AAV8-hOXR1 injection). ANOVA was used to determine the statistical significance. Data are represented as mean ± SE. * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001, **** P ≤ 0.0001.