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. 2021 Sep 7;13:6989–6998. doi: 10.2147/CMAR.S311526

Table 3.

Adverse Events

Adverse Events Any Grade, n(%) Grade 3 or 4, n(%)
Hypertension 74(43.3%) 2(1.2%)
Hand-foot-syndrome 67(39.2%) 10(5.8%)
Fatigue 59(34.5%) 6(3.5%)
Hepatic insufficiency 51(29.8%) 9(5.3%)
Hematological toxicity 51(29.8%) 19(11.1%)
Anorexia 43(25.1%) 9(5.3%)
Proteinuria 42(24.6%) 22(12.9%)
Diarrhea 39(22.8%) 1(0.6%)
Vomiting 25(14.6%) 2(1.2%)
Hoarse voice 23(13.5%) 2(1.2%)
Dry mouth 22(12.9%) 0