Table 1:
Aortic pathology and summary patient clinical characteristics grouped by clinical condition collated from electronic patient records and NHS blood and transplant service records
| Control | BAV | TAV | |
|---|---|---|---|
| Pathology: aetiology | |||
| Normal: coronary artery disease/healthy post-mortem tissue (n) | 4/9 | ||
| Aneurysm: bicuspid aortic valve (n) | 21 | ||
| Aneurysm: tricuspid aortic valve (n) | 23 | ||
|
Age (years), median (IQR) |
67 (19) |
66 (7) |
72 (15) |
| Sex | |||
| Male (n) | 9 | 12 | 12 |
| Female (n) | 4 | 9 | 11 |
|
Indexed aorta size, median (IQR) |
– |
11.5 (3.0) |
13.2 (8.0) |
| Diabetic | 0/4 | 0/21 | 1/23 |
| Hypertensive | 3/4 | 13/21 | 17/23 |
| Hypercholesterolemia | 3/4 | 11/21 | 17/23 |
| Family history of aneurysm | 0/4 | 3/21 | 3/23 |
Indexed aorta size is not available for control patients. Clinical characteristics for control patients reflect CABG patients only as this information is not available for NHS-BT tissue. Quantitative values are expressed as median and interquartile range (IQR).
BAV: bicuspid aortic valve; CABG: coronary artery bypass graft; NHS-BT: NHS blood and transplant service; SD: standard deviation; TAV: tricuspid aortic valve.