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. 2021 Sep 7;17:2867–2876. doi: 10.2147/NDT.S322507

Table 2.

Clinical Characteristics of Each Mood Episode

Total n=775 Mood Episode
Remission n=398 Depressive Episode n=268 Manic Episode n=50 Mixed Episode n=59
Sex, male(%) 65% 67% 69% 54% 47%
Age(SD) 44.4(8.9) 44.4(9.0) 44.3(8.7) 46.0(8.5) 43.6(8.8)
Psychiatric comorbidity 17% 14% 15% 22% 36%
Physical comorbidity 25% 21% 25% 32% 46%
Rapid cycling 9% 6% 9% 12% 21%
Psychotic symptom 5% 5% 6% 4% 8%
Suicide ideation 7% 0% 15% 0% 22%
Substance abuse 5% 3% 8% 6% 12%
Mood stabilizer prescriptions
 0 16% 12% 21% 10% 20%
 1 64% 69% 57% 62% 64%
 2 18% 16% 21% 28% 12%
 3 or more 2% 2% 1% 0% 3%
  Lithium 47% 50% 44% 56% 36%
  Valproic acid 27% 26% 25% 36% 37%
  Carbamazepine 3% 3% 3% 6% 3%
  Lamotrigine 28% 28% 31% 20% 22%
Antipsychotics prescriptions
 0 53% 57% 46% 64% 44%
 1 38% 34% 41% 30% 53%
 2 10% 9% 13% 6% 3%
 3 or more 0% 0% 0% 0% 0%
  Aripiprazole 11% 10% 12% 6% 17%
  Olanzapine 21% 18% 25% 14% 19%
  Quetiapine 11% 10% 13% 6% 10%
  Risperidone 2% 2% 2% 6% 2%
Antidepressant prescriptions
 0 56% 65% 42% 75% 55%
 1 34% 29% 46% 19% 44%
 2 9% 7% 11% 6% 2%
 3 or more 1% 0% 1% 0% 0%
Anxiolytics prescriptions
 0 65% 72% 54% 72% 64%
 1 31% 25% 40% 26% 34%
 2 4% 3% 5% 2% 2%
 3 or more 0% 0% 0% 0% 0%
Hypnotics prescriptions
 0 46% 54% 38% 40% 36%
 1 34% 29% 38% 34% 46%
 2 19% 16% 22% 26% 19%
 3 or more 1% 1% 1% 0% 0%
Bipolar Disorder Subcategories
 Type I 25% 27% 20% 34% 27%
 Type II 69% 67% 75% 62% 63%
 Unclassifiable 6% 5% 6% 4% 10%

Abbreviation: SD, standard deviation.