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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Contraception. 2021 Jun 19;104(4):327–336. doi: 10.1016/j.contraception.2021.06.010

Table III -.

Bleeding patterns in a 90-day reference period according to the ulipristal acetate dose released by a copper intrauterine system

Bleeding episodes in 90-day reference period 5 μg UPA/d N = 8 20 μg UPA/d N=10 40 μg UPA/d N=9
Frequency – n (%)
 Amenorrhea - - -
 Infrequent - 1 (10) 1 (11)
 Normal 8 (100) 9 (90) 8 (89)
 Frequent - - -
Duration – n (%)
 Prolonged - - -
 Not prolonged 8 (100) 10 (100) 9 (100)

UPA: ulipristal acetate

Per protocol population includes all participants who completed 12 weeks of intrauterine system use (n=27)

Amenorrhea: no bleeding or spotting (B/S) episodes in a 90-day reference period (RP); Infrequent: <3 B/S episodes in a 90-day RP; Normal frequency: 3–5 B/S episodes in a 90-day RP; Frequent: >5 B/S episodes in a 90-day RP.