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. Author manuscript; available in PMC: 2022 Sep 15.
Published in final edited form as: Neuropharmacology. 2021 Jul 8;196:108702. doi: 10.1016/j.neuropharm.2021.108702

Figure 5. LH β adrenergic receptor activation blunts binge-like ethanol intake in female C57BL6/J mice.

Figure 5.

β agonism via xamoterol hemifumerate (XAM) blunted binge-like ethanol intake (A) and BECs (B) in females exclusively without altering sucrose intake (C; n=6 female, 7 male). Approximate cannula placements within the LH (D). (E) Further analyses of ethanol intake data indicated, when collapsed across sexes, no significant differences between vehicle and XAM treatment in mice with High baseline ethanol intake (upper 50% of a median-split) or mice with Low baseline intake (lower 50% of a median-split). All values represent mean ± SEM. % represents significant interaction following two-way ANOVA as determined via Bonferroni post-hoc testing.