Table 2.

Summary of selected cellular and molecular changes related to memory formation in the dorsal hippocampus after experimental interventions in the BLA in rodents.

BLA intervention	Hippocampal changes	References
Infusion of the β-adrenoreceptor agonist clenbuterol	Increased hippocampal ARC in rats trained on IA or high-arousal OR	McIntyre et al., 2005 McReynolds et al., 2014
Optogenetic stimulation of the BLA-entorhinal cortex pathway after spatial training	Increased Arc expression in the hippocampus in male rats	Wahlstrom et al., 2021
Infusion of muscimol into the BLA before contextual fear conditioning	Muscimol inactivation of the BLA attenuates increases in hippocampal Arc and c-fos mRNA associated with contextual fear conditioning	Huff et al., 2006
Infusion of the HDAC inhibitor TSA into the BLA at different time intervals after IA training	Increases in BDNF levels in the dorsal hippocampus, accompanied by memory enhancement with infusions given between 1.5 and 6 h posttraining	Valiati et al., 2017
Infusion of midazolam before contextual fear conditioning	Blockade of dendritic spine remodeling in the hippocampus accompanied by impairment in contextual fear conditioning	Giachero et al., 2015
Infusion of the GABAA receptor antagonist bicuculine before contextual fear conditioning	Facilitation of both hippocampal synaptic structural remodeling and contextual fear conditioning	Giachero et al., 2015
Inhibition through viral vector-mediated overexpression of an outwardly rectifying potassium	Prevention of immature newborn neuron activation in response to a fear-conditioning task	Kirby et al., 2012

See main article text for abbreviation definitions.