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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Am J Obstet Gynecol MFM. 2021 May 13;3(5):100395. doi: 10.1016/j.ajogmf.2021.100395

TABLE 2.

Maternal outcomes

Outcome No anemia (n=156,349) Anemia (n=10,217) P value
SMM composite outcomea (n=166,566) 6269 (4.0)b 761 (7.5)b <.001b
 Maternal death (n=134,620) 7 (0.01)b 4 (0.04)b <.001b
 Eclampsia (n=166,566) 142 (0.1)b 19 (0.2)b .003b
 Postpartum thrombosis (n=110,635) 66 (0.1)b 18 (0.2)b <.001b
 Antepartum thrombosis (n=134,576) 329 (0.3)b 58 (0.6)b <.001b
 Transfusion during labor (n=110,635) 977 (1.0)b 246 (2.9)b <.001b
 Transfusion postpartum (n=130,427) 4557 (3.7)b 563 (6.7)b <.001b
 Hysterectomy (n=166,566) 79 (0.1)b 30 (0.3)b <.001b
 Maternal ICU admission (n=166,565) 868 (0.6) 64 (0.6) .350
SMM composite without transfusion (n=110,635) 697 (0.7)b 156 (1.8)b <.001b
Blood loss (mL) (n=118,081) 451.1±257.0b 617.0±10,531.0b <.001b
Postpartum hemorrhage (n=166,566) 10,785 (6.9)b 1405 (13.8)b <.001b
Preeclampsia or eclampsia or HELLP (n=166,566) 5856 (3.8)b 565 (5.5)b <.001b
Cesarean delivery (n=166,566) 44,416 (28.4)b 3754 (36.7)b <.001b
Composite infectious morbidityc (n=166,566) 5027 (3.2)b 378 (3.7)b .007b
 Wound infection (n=110,635) 564 (0.6)b 90 (1.1)b <.001b
 Antepartum chorioamnionitis (n=93,431) 1052 (1.2)b 144 (2.3)b <.001b
 Intrapartum chorioamnionitis (n=166,565) 4169 (2.7) 261 (2.6) .496
 Endometritis (n=67,754) 498 (0.8) 49 (0.8) .801
GA at delivery (n=166,566) 38.5±2.3 38.5±2.4 .358
Preterm delivery (n=166,566) 18,716 (12.0)b 1318 (12.9)b .005b

Data are presented as number (percentage) or mean±standard deviation.

GA, gestational age; HELLP, hemolysis, elevated liver enzymes, low platelet count; ICU, intensive care unit; SMM, severe maternal morbidity.

a

Composite includes maternal death, eclampsia, thrombosis, transfusion, hysterectomy, and ICU admission;

b

Denotes statistical significance;

c

Composite includes wound infection, chorioamnionitis, and endometritits.