TABLE 2.
Outcome | No anemia (n=156,349) | Anemia (n=10,217) | P value |
---|---|---|---|
SMM composite outcomea (n=166,566) | 6269 (4.0)b | 761 (7.5)b | <.001b |
Maternal death (n=134,620) | 7 (0.01)b | 4 (0.04)b | <.001b |
Eclampsia (n=166,566) | 142 (0.1)b | 19 (0.2)b | .003b |
Postpartum thrombosis (n=110,635) | 66 (0.1)b | 18 (0.2)b | <.001b |
Antepartum thrombosis (n=134,576) | 329 (0.3)b | 58 (0.6)b | <.001b |
Transfusion during labor (n=110,635) | 977 (1.0)b | 246 (2.9)b | <.001b |
Transfusion postpartum (n=130,427) | 4557 (3.7)b | 563 (6.7)b | <.001b |
Hysterectomy (n=166,566) | 79 (0.1)b | 30 (0.3)b | <.001b |
Maternal ICU admission (n=166,565) | 868 (0.6) | 64 (0.6) | .350 |
SMM composite without transfusion (n=110,635) | 697 (0.7)b | 156 (1.8)b | <.001b |
Blood loss (mL) (n=118,081) | 451.1±257.0b | 617.0±10,531.0b | <.001b |
Postpartum hemorrhage (n=166,566) | 10,785 (6.9)b | 1405 (13.8)b | <.001b |
Preeclampsia or eclampsia or HELLP (n=166,566) | 5856 (3.8)b | 565 (5.5)b | <.001b |
Cesarean delivery (n=166,566) | 44,416 (28.4)b | 3754 (36.7)b | <.001b |
Composite infectious morbidityc (n=166,566) | 5027 (3.2)b | 378 (3.7)b | .007b |
Wound infection (n=110,635) | 564 (0.6)b | 90 (1.1)b | <.001b |
Antepartum chorioamnionitis (n=93,431) | 1052 (1.2)b | 144 (2.3)b | <.001b |
Intrapartum chorioamnionitis (n=166,565) | 4169 (2.7) | 261 (2.6) | .496 |
Endometritis (n=67,754) | 498 (0.8) | 49 (0.8) | .801 |
GA at delivery (n=166,566) | 38.5±2.3 | 38.5±2.4 | .358 |
Preterm delivery (n=166,566) | 18,716 (12.0)b | 1318 (12.9)b | .005b |
Data are presented as number (percentage) or mean±standard deviation.
GA, gestational age; HELLP, hemolysis, elevated liver enzymes, low platelet count; ICU, intensive care unit; SMM, severe maternal morbidity.
Composite includes maternal death, eclampsia, thrombosis, transfusion, hysterectomy, and ICU admission;
Denotes statistical significance;
Composite includes wound infection, chorioamnionitis, and endometritits.