. Author manuscript; available in PMC: 2022 Sep 1.

Published in final edited form as: Am J Obstet Gynecol MFM. 2021 May 13;3(5):100395. doi: 10.1016/j.ajogmf.2021.100395

TABLE 5.

Association of maternal anemia with neonatal outcomes

Neonatal outcome	Unadjusted OR	95% CI	Adjusted OR^a	95% CI
Composite neonatal outcome^b	1.20^c	1.13–1.27^c	1.14^c	1.06–1.23^c
5-min Apgar score of <7	1.24^c	1.08–1.42^c	1.21	1.00–1.47
HIE	1.23	0.29–5.20	1	––
RDS	0.88^c	0.78–0.99^c	0.97	0.83–1.12
NEC	1.30	0.86–1.97	1.14	0.65–2.03
Seizures	1.19	0.79–1.82	1.13	0.64–1.99
ICH	0.86	0.58–1.28	0.88	0.52–1.49
Neonatal sepsis	1.06	0.94–1.20	1.14	0.97–1.33
PVH or IVH	1.05	0.81–1.36	1.20	0.84–1.69
Neonatal death	0.67	0.44–1.03	0.70	0.39–1.26
NICU admission	1.22^c	1.15–1.29^c	1.16^c	1.07–1.25^c
Antenatal fetal distress	1.60^c	1.48–1.72^c	1.15^c	1.02–1.30^c
Intrapartum fetal distress	1.21^c	1.12–1.30^c	0.98	0.88–1.09
Birthweight <2500 g	1.10^c	1.03–1.18^c	1.03	0.94–1.14
Neonatal anemia or transfusion	1.07	0.93–1.22	1.10	0.91–1.31
Neonatal anemia	1.10	0.96–1.26	1.12	0.93–1.34
Neonatal transfusion	0.39^c	0.17–0.87^c	0.50	0.18–1.36

CI, confidence interval; HIE, hypoxic ischemic encephalopathy; ICH, intracranial hemorrhage; NEC, necrotizing enterocolitis; NICU, neonatal intensive care unit; OR, odds ratio; PVH or IVH, periventricular or intraventricular hemorrhage; RDS, respiratory distress syndrome.

Controlled for body mass index, nulliparity, maternal age, maternal race, marital status, insurance, diabetes, asthma, history of cesarean delivery, alcohol use;

Composite includes 5-minute Apgar score of <7, HIE, RDS, NEC, seizures, ICH, neonatal sepsis, PVH or IVH, neonatal death, and NICU admission;

Denotes statistical significance.