Table 2.

Forward stepwise regression of factors associated with severe symptom(s)

	Step 1	Step 2	Step 3	Step 4	Step 5
	OR (95%CI)	OR (95%CI)	OR (95%CI)	OR (95%CI)	OR (95%CI)
Liver Frailty Index †	1.4 (1.2–1.7)	1.4 (1.1–1.7)	1.3 (1.1–1.6)	1.3 (1.1–1.6)	1.3 (1.1–1.6)
MELDNa		1.1 (1.0–1.1)	1.1 (1.0–1.1)	1.1 (1.0–1.1)	1.1 (1.0–1.1)
Ascites			1.6 (0.7–3.4)	1.5 (0.7–3.2)	1.5 (0.7–3.3)
Hepatic encephalopathy				1.4 (0.7–2.9)	1.4 (0.7–2.9)
Age					1.0 (1.0–1.0)

^†per 0.5-unit increase

MELDNa=Model for End-Stage Liver Disease–sodium, CI=confidence ratio, OR= Odds ratio