Fig. 2.
The sitting less and exercise regimens improve insulin sensitivity compared with the sitting regimen. Regimens for sitting, sitting less and exercise are denoted as SIT, SL and EXE, respectively. Data are shown by boxplots in which each participant is represented by a particular symbol throughout the fig. A hyperinsulinaemic–euglycaemic two-step clamp was performed to assess insulin sensitivity. (a) Whole-body insulin-stimulated glucose disposal during high-dose insulin infusion expressed as Rd (n = 10). (b) NOGD during high-dose insulin infusion (n = 10). (c) Suppression of hepatic EGP during low-dose insulin infusion (n = 11). (d) IHL measured by 1H-MRS (n = 10). *p < 0.05 and **p < 0.01. Boxplots: box includes the IQR corresponding to 25th percentile (Q1, bottom of box), 50th percentile (Q2, bold line within box, i.e. the median) and 75th percentile (Q3, top of box) of the data. The bottom whisker is set at Q1 – 1.5 × IQR and the top whisker at Q3 + 1.5 × IQR