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FISH signal distribution of chromosome 8 subregion in zygotenea of mice with different genotypes
| Genotype | Signal distribution
|
||
|---|---|---|---|
| Separated | Aligned | Fused | |
| Control | 0 | 22 | 78 |
| Atm−/− | 24b | 28 | 52 |
Stages were assigned according to chromatin morphology (26). Pairing of the chromosome 8 subterminal region is reduced in Atm−/− mice.
Separated signals in Atm−/− mice are significantly different from those in control mice by chi-square analysis (P < 0.05).
