Table 9.

Penalized Logistic Regression^† Model for Odds of Post-operative Complication, by Obesity Status (Reference, Non-obese)

Complication	OR (95 % CI)	P
Breast Complication
Total Flap Loss	11.21 (0.58–2143.39)	0.12
Partial Flap Loss	0.87 (0.20– 3.34)	0.84
Free-Flap Necrosis	0.82 (0.05 – 7.79)	0.87
Fat Necrosis	0.77 (0.43 – 1.35)	0.36
Mastectomy Skin-Flap Necrosis	2.87 (1.65 – 5.06)	< 0.01*
Hematoma	0.74 (0.31 – 1.67)	0.48
Seroma	0.98 (0.27– 3.26)	0.98
Major Infection	1.38 (0.31 – 6.61)	0.67
Minor Infection (Cellulitis)	1.19 (0.35 – 3.83)	0.77
Delayed Wound Healing	1.00 (0.23 – 3.87)	0.99
Donor-Site Complication
Delayed Wound Healing	1.41 (0.55 – 3.61)	0.47
Wound Dehiscence	5.53 (1.33 – 32.28)	0.02*
Infection	1.40 (0.36 – 5.06)	0.61
Seroma	1.22 (0.25 – 5.94)	0.80
Abdominal Hernia or Bulge	1.01 (0.41 – 2.36)	0.99

OR, odds ratio; CI, confidence interval

^*Statistically significant (p < 0.05).

^†Each model included the following covariates: age at surgery, timing of reconstruction (immediate v. delayed), flap type (msTRAM v. perforator), laterality (unilateral v. bilateral), neoadjuvant chemotherapy, history of smoking, Charlson comorbidity index, and history of pre-operative radiation.