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. 2021 Jul 22;22(15):7815. doi: 10.3390/ijms22157815

Figure 5.

Figure 5

Retinal structure analysis in P23H/+:Tlr2+/− and P23H/+:Tlr2−/− mice. (A) Representative images of peripheral, medial, and central retinal areas in cryosections from 4-month-old P23H/+:Tlr2+/− and P23H/+:Tlr2−/− mice. Nuclei were stained with DAPI (blue). ONL, outer nuclear layer; INL, inner nuclear layer; GCL, ganglion cell layer. Scale bar: 31 μm. (B) ONL and INL thickness were measured in equatorial sections corresponding to the peripheral, medial, and central retina (see Methods section). The number of photoreceptor rows was also scored in these same regions. Dots represent individual mice and bars represent the mean (+SEM) for each group. n = 6–11 animals per group (5 sections per retina, 2 images per section in each area, 3 measurements per image). * p < 0.05 (Mann-Whitney U-test).