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Schematic representation of the CRISPR/Cas9 gene editing mechanism. gRNA directs Cas9 to cleave the target sequence upstream of the protospacer adjacent motif (PAM), producing a double‐stranded break (DSB). The DSB is subsequently repaired either by nonhomologous end‐joining (NHEJ) or by homology‐directed repair (HDR). Repair via NHEJ produces indels (knockout), whereas repair through HDR results in knockin
