Table 1.
Patients’ characteristics in alive and dead groups.
| Feature | Group |
Group |
|||||
|---|---|---|---|---|---|---|---|
| Alive (n = 2586) | Dead (n = 1146) | p | COV (n = 3110) | COV + AD (n = 363) | COV + PD (n =259) | p | |
| Intubation (%) | 75 (2.9) | 514 (44.9) | < 0.001* | 476 (15.3) | 67 (18.5) | 46 (17.8) | 0.197 |
| Mean (SD) age (year) | 76.1 (10.1) | 79.7 (8.3) | < 0.001* | 77.2 (9.7) | 80.2 (7.9) | 73 (10.5) | 0.001* |
| Woman (%) | 978 (37.8) | 420 (36.6) | 0.519 | 1165 (37.5) | 153 (42.1) | 80 (30.9) | 0.017* |
| Mean (SD) PaO2 (mmHg) | 88.4 (7.9) | 81.9 (13.1) | < 0.001* | 86.5 (10.2) | 85.5 (10.7) | 86.3 (9.7) | 0.271 |
| O2 therapy early at admission (%) | 1293 (50.0) | 687 (59.9) | < 0.001* | 1635 (52.6) | 215 (59.2) | 130 (50.2) | 0.035* |
| Respiratory Rate (%) | |||||||
| < 14 | 4 (0.2) | 13 (1.1) | < 0.001* | 14 (0.5) | 2 (0.6) | 1 (0.4) | 0.921 |
| 14–18 | 669 (25.9) | 246 (21.5) | 770 (24.8) | 83 (22.9) | 62 (23.9) | ||
| 18–22 | 1417 (54.8) | 560 (48.9) | 1656 (53.2) | 188 (51.8) | 133 (51.4) | ||
| 22–28 | 431 (16.7) | 263 (22.9) | 564 (18.1) | 76 (20.9) | 54 (20.8) | ||
| > 28 | 65 (2.5) | 64 (5.6) | 106 (3.4) | 14 (3.9) | 9 (3.5) | ||
| Mean (SD) Temperature (°C) | 37.2 (1.6) | 37.2 (0.7) | 0.785 | 37.2 (1.5) | 37.2 (0.7) | 37.3 (0.7) | 0.989 |
| Fever (%) | 837 (32.4) | 382 (33.3) | 0.587 | 1004 (32.3) | 121 (33.3) | 94 (36.3) | 0.4 |
| Loss of Consciousness (%) | 153 (5.9) | 210 (18.3) | < 0.001* | 238 (7.7) | 81 (22.3) | 44 (17) | < 0.001* |
| Respiratory Distress (%) | 1451 (56.1) | 813 (70.9) | < 0.001* | 1911 (61.4) | 202 (55.6) | 151 (58.3) | 0.073 |
| Myalgia (%) | 803 (31.1) | 305 (26.6) | 0.007* | 997 (32.1) | 59 (16.3) | 52 (20.1) | < 0.001* |
| Cough (%) | 1105 (42.7) | 486 (42.4) | 0.883 | 1383 (44.5) | 125 (34.4) | 83 (32.0) | < 0.001* |
| Systolic Hypertension (%) | 821 (31.7) | 410 (35.8) | 0.017* | 1019 (32.8) | 117 (32.2) | 95 (36.7) | 0.415 |
| Nausea (%) | 219 (8.5) | 75 (6.5) | 0.052† | 268 (8.6) | 13 (3.6) | 13 (5.0) | < 0.001* |
| Anorexia (%) | 397 (15.4) | 150 (13.1) | 0.08 | 459 (14.8) | 53 (14.6) | 35 (13.5) | 0.862 |
| Headache (%) | 218 (8.4) | 57 (5.0) | < 0.001* | 252 (8.1) | 10 (2.8) | 13 (5.0) | < 0.001* |
| Diabetes (%) | 529 (20.5) | 268 (23.4) | 0.049* | 672 (21.6) | 80 (22) | 45 (17.4) | 0.264 |
| Cardiovascular Disease (%) | 470 (18.2) | 274 (23.9) | < 0.001* | 640 (20.6) | 57 (15.7) | 47 (18.1) | 0.067† |
| Positive Contact History (%) | 1203 (46.5) | 537 (46.9) | 0.876 | 1452 (46.7) | 170 (46.8) | 118 (45.6) | 0.937 |
| Mean (SD) Start of symptoms before admission (days) | 5.6 (3.9) | 5.3 (4.1) | 0.042* | 5.5 (3.9) | 5.4 (4.4) | 5.7 (4.5) | 0.594 |
| COV (%) | 2191 (84.7) | 919 (80.2) | < 0.001* | ||||
| COV + AD (%) | 227 (8.8) | 136 (11.9) | 0.004* | ||||
| COV + PD (%) | 168 (6.5) | 91 (7.9) | 0.127 | ||||
Categorical variables were compared with χ2, and continuous variables were compared with t-test for independent samples between alive and dead groups, and with ANOVA test among COV, COV + AD, and COV + PD groups. SD: Standard Deviation; PaO2: Partial Pressure of Oxygen; COV: Patient with a confirmed diagnosis of COVID-19 infection; AD: Alzheimer's Disease; PD: Parkinson's Disease.
*
Significant at p < 0.05.
†
Approaching significance.