Table 1. Demographics and clinical data for STK11m and STK11w stage III NSCLC.
| Variable | Level | Total, N=70, n (%) | STK11, n (%) | ||
|---|---|---|---|---|---|
| STK11w, N=59 | STK11m, N=11 | P value | |||
| Sex | F | 35 (50.0) | 31 (52.5) | 4 (36.4) | 0.32 |
| M | 35 (50.0) | 28 (47.5) | 7 (63.6) | ||
| Age | ≤65 years | 41 (58.6) | 32 (54.2) | 9 (81.8) | 0.11 |
| >65 years | 29 (41.4) | 27 (45.8) | 2 (18.2) | ||
| Smoking history | Current | 65 (92.9) | 54 (91.5) | 11 (100) | 1.00 |
| Never smoker | 5 (7.1) | 5 (8.5) | 0 (0) | ||
| ECOG | 0–1 | 60 (85.7) | 49 (83.1) | 11 (100) | 0.34 |
| 2–3 | 10 (14.3) | 10 (16.9) | 0 (0) | ||
| Histology | Non-squamous | 45 (64.3) | 37 (62.7) | 8 (72.7) | 0.73 |
| Squamous | 25 (35.7) | 22 (37.3) | 3 (27.3) | ||
| Stage | IIIA | 38 (54.3) | 32 (54.2) | 6 (54.5) | 0.98 |
| IIIB/C | 32 (45.7) | 27 (45.8) | 5 (45.5) | ||
| KRAS | No | 56 (80.0) | 48 (81.4) | 8 (72.7) | 0.68 |
| Yes | 14 (20.0) | 11 (18.6) | 3 (27.3) | ||
| TP53 | No | 49 (70.0) | 44 (74.6) | 5 (45.5) | 0.07 |
| Yes | 21 (30.0) | 15 (25.4) | 6 (54.5) | ||
| PD-L1 | <1% | 21 (52.5) | 16 (50.0) | 5 (62.5) | 0.66 |
| 1–50% | 8 (20.0) | 6 (18.8) | 2 (25.0) | ||
| >50% | 11 (27.5) | 10 (31.3) | 1 (12.5) | ||
| Missing | 30 | 27 | 3 | ||
| ICI consolidation | No | 47 (67.1) | 42 (71.2) | 5 (45.5) | 0.16 |
| Yes | 23 (32.9) | 17 (28.8) | 6 (54.5) | ||
| Cycles of ICI | N | 70 | 59 | 11 | 0.10 |
| Median | 0 | 0 | 3 | ||
| Range | (0-25) | (0-25) | (0-17) | ||
NSCLC, non-small cell lung cancer.