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. 2021 Sep 7;14:5313–5322. doi: 10.2147/IJGM.S319717

Table 2.

Univariate and Multivariate Logistic Regression Analysis for the Association Between Hypophosphatemia and Mortality in Included COVID-19 Patients

Variables Unadjusted Analysis Adjusted Analysis
OR 95% Cl p OR 95% Cl p
Age (years) 1.088 1.064–1.112 <0.001 1.059 1.030–1.088 <0.001
Male 1.659 1.017–2.705 0.042
Hypertension 4.163 2.427–7.140 <0.001
Diabetes mellitus 1.696 0.688–4.182 0.252
COPD 6.068 2.608–14.119 <0.001
Chronic liver disease 2.318 0.843–6.374 0.103
Malignancy 4.571 0.905–23.081 0.066
Oxygen saturation 0.741 0.678–0.808 <0.001 0.733 0.645–0.834 <0.001
WBCs 1.365 1.256–1.484 <0.001 1.428 1.277–1.597 <0.001
Neutrophils 1.002 0.996–1.009 0.496
Lymphocytes 0.037 0.016–0.083 <0.001 0.075 0.026–0.220 <0.001
Monocytes 0.523 0.175–1.563 0.246
Platelets 0.991 0.987–0.994 <0.001
Hemoglobin 1.005 0.990–1.019 0.534
Albumin 0.766 0.713–0.824 <0.001
Immunoglobulin 1.031 0.985–1.079 0.192
ALT 1.005 0.998–1.011 0.163
AST 1.022 1.012–1.031 <0.001
Serum creatinine 1.011 1.005–1.017 0.001
Hypophosphatemia 7.587 3.612–15.936 <0.001 3.636 1.285–10.288 0.015
Severity <0.001
Mild 1 Reference
Moderate 5.38×107 0.999
Severe 4.86×108 0.998
Critical 6.63×108 0.998

Abbreviations: COPD, chronic obstructive pulmonary disease; WBC, white blood cell; ALT, alanine aminotransferase; AST, aspartate aminotransferase.