Table 2.

Risk factors for patients with LARC

Factors	Univariate logistic regression		Multivariate logistic regression
	OR (95% CI)	P value	OR (95% CI)	P value
Age	1.01 (0.98–1.04)	0.484	Not selected	Not selected
Gender	1.40 (0.69–2.84)	0.352	Not selected	Not selected
Tumor diameter	2.14 (1.60–2.87)	< 0.001	0.99 (0.68–1.43)	0.937
Location	2.02 (1.09–3.75)	0.026	1.47 (0.67–3.22)	0.339
Differentiation degree	0.71 (0.39–1.27)	0.249	Not selected	Not selected
CEA level	4.08 (1.85–9.00)	< 0.001	2.68 (1.03–7.00)	0.044
CA199 level	5.83 (1.33–25.62)	0.019	1.95 (0.39–9.66)	0.416
Rad-score	8.41 (4.31–16.38)	< 0.001	7.45 (3.12–17.75)	< 0.001

P values with statistical significance are shown in bold

LARC locally advanced rectal cancer, OR odds ratio, CI confidence interval, CEA carcinoembryonic antigen, CA199 carbohydrate antigen 199