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. 2021 Jun 16;46(10):4647–4659. doi: 10.1007/s00261-021-03010-1

Table 1.

Pre-defined settings for study ultrasound scanners

Ultrasound scanner Mechanical Index (MI) Frequency Frame rate Depth Focus
Sonazoid SonoVue
GE LOGIQ E9 0.15–0.31 0.06–0.2 (Gen), (Res) or adjust according to patient 9–11 Hz Adjust according to lesion depth

Place focus at the bottom of the lesion, and ideally at

the bottom of the field of view

Philips iU22 0.18–0.19 0.06–0.07

Gen/Pen/Res/HRes/CGen/CRes/CPen (Or patient

dependent)

9–10 Hz
Toshiba Aplio 500 0.15–0.18 0.07–0.08 3.0 h, 3.5 h 5 Hz

Due to the lack of standardization in calculating MI, the scanners have different optimal MI settings