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. 2021 Aug 30;12:737630. doi: 10.3389/fphar.2021.737630

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Copyright © 2021 Chen, Zhao, Wei, Ma, Liu, Li, Jing, Wang and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Potential metabolites changes in ANIT-induced cholestatic liver injury with PF treatment. (A) 3-Methoxytyramine; (B) 5-L-Glutamyl-taurine; (C) Homovanillic acid; (D) UDP-D-Xylose; (E) L-Dopa; (F) Linoleic acid; (G) L-Phenylalanine; (H) N-Desmethylcitalopram; (I) PE [15:0/18:4 (6Z,9Z,12Z,15Z)]; (J) Phosphocreatine; (K) Sepiapterin; (L) Taurochenodesoxycholic acid. Data were presented as means ± SD (n = 6). ^## p < 0.01, ^# p < 0.05 compared with the control group, ^** p < 0.01, ^* p < 0.05 compared with ANIT group.