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. 2021 Sep 13;11(6):611–628. doi: 10.1007/s13659-021-00317-w

Table 2.

Diarylheptanoids

Compound name Plant species Level of activity Predicted or known target of virus Mode of action or other activities References
Hirsutenone (9) Alnus japonica IC50 = 4.1 ± 0.3 μM SARS-CoV3 PLpro [25]
Hirsutanonol (10) Alnus japonica IC50 = 7.8 ± 1.7 μM SARS-CoV3 PLpro [25]
Rubranoside B (11) Alnus japonica IC50 = 8.0 ± 0.2 μM SARS-CoV3 PLpro [25]
Rubranoside A (12) Alnus japonica IC50 = 9.1 ± 1.0 μM SARS-CoV3 PLpro [25]
Curcumin (13) Curcuma longa IC50 = 5.7 μM SARS-CoV3 PLpro [25]