Table 2.
Sex-specific relative risks of thyroid cancer incidence in China due to age, period, and cohort effects.
| Factor | Males | Females | ||
|---|---|---|---|---|
| RR (95% CI) | P value | RR (95% CI) | P value | |
| Age | ||||
| 5–9 | 0.26 (0.03–2.21) | 0.217 | 0.25 (0.05–1.26) | 0.093 |
| 10–14 | 0.21 (0.03–1.54) | 0.125 | 0.28 (0.07–1.08) | 0.064 |
| 15–19 | 0.28 (0.05–1.52) | 0.139 | 0.26 (0.07–0.99) | 0.048 |
| 20–24 | 0.39 (0.09–1.68) | 0.206 | 0.43 (0.15–1.22) | 0.113 |
| 25–29 | 0.66 (0.20–2.19) | 0.493 | 0.66 (0.28–1.56) | 0.342 |
| 30–34 | 0.81 (0.27–2.45) | 0.706 | 1.29 (0.66–2.51) | 0.459 |
| 35–39 | 1.04 (0.38–2.86) | 0.942 | 1.44 (0.78–2.66) | 0.245 |
| 40–44 | 1.53 (0.64–3.67) | 0.338 | 2.18 (1.30–3.63) | 0.003 |
| 45–49 | 2.06 (0.97–4.38) | 0.061 | 1.52 (0.90–2.54) | 0.114 |
| 50–54 | 2.66 (1.40–5.06) | 0.003 | 1.72 (1.08–2.72) | 0.021 |
| 55–59 | 3.11 (1.78–5.42) | <0.001 | 1.80 (1.17–2.75) | 0.007 |
| 60–64 | 1.52 (0.80–2.88) | 0.201 | 1.90 (1.26–2.86) | 0.002 |
| 65–69 | 1.48 (0.80–2.76) | 0.212 | 1.80 (1.17–2.76) | 0.007 |
| 70–74 | 1.51 (0.80–2.83) | 0.2 | 1.79 (1.13–2.84) | 0.013 |
| 75–79 | 3.42 (1.86–6.28) | <0.001 | 1.72 (1.02–2.91) | 0.044 |
| Period | ||||
| 1994 | 0.44 (0.23–0.82) | 0.009 | 0.70 (0.48–1.01) | 0.056 |
| 1999 | 0.57 (0.34–0.95) | 0.032 | 0.81 (0.59–1.11) | 0.192 |
| 2004 | 0.85 (0.55–1.31) | 0.457 | 0.94 (0.71–1.25) | 0.681 |
| 2009 | 1.32 (0.90–1.94) | 0.16 | 1.11 (0.85–1.46) | 0.447 |
| 2014 | 1.78 (1.21–2.62) | 0.003 | 1.20 (0.90–1.61) | 0.206 |
| 2019 | 2.02 (1.33–3.08) | 0.001 | 1.40 (1.03–1.90) | 0.032 |
| Cohort | ||||
| 1915–1919 | 2.18 (0.56–8.43) | 0.26 | 1.81 (0.63–5.22) | 0.275 |
| 1920–1924 | 1.99 (0.68–5.84) | 0.208 | 1.52 (0.69–3.37) | 0.299 |
| 1925–1929 | 1.90 (0.81–4.48) | 0.141 | 1.48 (0.78–2.81) | 0.226 |
| 1930–1934 | 1.73 (0.86–3.48) | 0.126 | 1.44 (0.84–2.47) | 0.181 |
| 1935–1939 | 1.47 (0.82–2.64) | 0.198 | 1.41 (0.88–2.26) | 0.154 |
| 1940–1944 | 1.19 (0.70–2.03) | 0.511 | 1.32 (0.86–2.03) | 0.208 |
| 1945–1949 | 1.05 (0.55–2.00) | 0.885 | 1.38 (0.88–2.16) | 0.167 |
| 1950–1954 | 0.98 (0.49–1.99) | 0.958 | 1.34 (0.83–2.18) | 0.231 |
| 1955–1959 | 0.96 (0.45–2.06) | 0.911 | 1.24 (0.72–2.13) | 0.435 |
| 1960–1964 | 0.92 (0.40–2.10) | 0.837 | 1.17 (0.64–2.13) | 0.606 |
| 1965–1969 | 0.90 (0.35–2.30) | 0.819 | 1.12 (0.57–2.17) | 0.747 |
| 1970–1974 | 0.81 (0.28–2.39) | 0.707 | 1.01 (0.49–2.12) | 0.969 |
| 1975–1979 | 0.83 (0.25–2.73) | 0.764 | 0.96 (0.43–2.14) | 0.917 |
| 1980–1984 | 0.85 (0.24–3.10) | 0.809 | 0.86 (0.35–2.13) | 0.753 |
| 1985–1989 | 0.85 (0.22–3.32) | 0.818 | 0.74 (0.27–2.03) | 0.558 |
| 1990–1994 | 0.75 (0.16–3.55) | 0.721 | 0.61 (0.17–2.20) | 0.447 |
| 1995–1999 | 0.70 (0.11–4.37) | 0.702 | 0.56 (0.12–2.67) | 0.468 |
| 2000–2004 | 0.63 (0.07–5.66) | 0.683 | 0.54 (0.08–3.57) | 0.525 |
| 2005–2009 | 0.57 (0.04–8.91) | 0.689 | 0.51 (0.05–4.98) | 0.559 |
| 2010–2014 | 0.53 (0.01–33.91) | 0.762 | 0.52 (0.01–19.19) | 0.724 |
| Deviance | 0.43 | 1.44 | ||
| AIC | 2.88 | 3.48 | ||
| BIC | −233.56 | −232.55 |
RR denotes the relative risk of thyroid cancer incidence in a particular age, period, or birth cohort relative to the average level of all age, period, or birth cohort combined. RR, relative risk; CI, confidence interval; AIC, Akaike information criterion; BIC, Bayesian information criterion.