Figure 4.

Cell cycle and cell death associated genes are enriched in Ddb1-deficient T cells. (A) Volcano plots of the differentially expressed genes (DEGs) in Ddb1-TaKO SMARTA CD4⁺ T cells relative to the expression in WT SMARTA CD4⁺ T cells, by RNA-seq analysis of Ddb1-TaKO SMARTA CD4⁺ T cells and WT SMARTA CD4⁺ T cells isolated from B6 mice 5d after transfer of SMARTA cells and infection of hosts with LCMV Armstrong. (B) The KEGG pathway enrichment analysis of DEGs from mice in (A). (C, D) Heat map of selected genes of DEGs from mice in (A).