FIGURE 3.

– LPS induced acute lung injury. (A) LPS injury assessment in LysM-cre ^- mice. LysM-cre ^- mice received either PBS or 10 µg LPS and were retrieved 24 h later. (B) Effect of myeloid cell Gal-3 depletion on LPS-induced lung inflammation. 10µg LPS was administered i. t. to LysM-cre ^- and LysM-cre ⁺ mice and retrieved at 24 or 48 h. Injury levels were analysed via histological inflammation score, tissue digest and BAL assessment. (C) BAL total neutrophils in LysM-cre ^-, LysM-cre ⁺ and Gal-3 ^−/− mice following 24 h LPS or saline control. Data represented as mean ± SEM. Analysed via students t-test (n = 4–5, **p < 0.01, ***p < 0.001). Images taken at x200.